CBD oil Bioavailability: how to get the most out of your dose

When it comes to CBD, it's essential to know the phrase "bioavailability," which is defined as "the degree to which a medicine or other substance is absorbed or becomes available at the site of physiological action after administration".

But what exactly does that imply, and why is it important in the context of CBD?

Let’s find out!




The term "bioavailability" refers to the amount of a substance that is absorbed into your bloodstream and at what rate.

The most important aspect of knowing a substance's bioavailability is determining how much of it you should use.

Knowing how bioavailable something is can help you figure out how successful it will be at producing the desired results.

The bioavailability of CBD oil is largely determined by the method of administration you pick-how you take CBD.

CBD can be used in a variety of ways, ranging from edibles and gummies to topical applications and vapes. The bioavailability of each of these methods is different.


CBD Oil Bioavailability


When taken by ingestion, CBD usually passes through the digestive system after being swallowed.

After that, it typically makes its way to your hepatic portal, where it is mostly broken down by necessary liver enzymes.

The good news is that CBD oil can be consumed in a variety of ways other than orally (by swallowing).

You can avoid the first-pass effect by using alternative delivery techniques.

Although it may seem like a little distinction, putting CBD oil under your tongue improves its bioavailability.

This is because CBD is absorbed directly into the bloodstream by small capillaries under the tongue.

That is why CBD tinctures and oils should be taken sublingually and held for at least a minute before swallowing.

Bypassing the liver and digestive system, this route of CBD administration allows the molecule to be digested by your enzymes rather than the liver and digestive system.

When you take CBD sublingually, it gets into your bloodstream faster and has a higher bioavailability than when you take it in edible form.

Many people have a bad habit of putting CBD oil into their drinks and consuming it that way. You shouldn’t be doing this because the effects will not be the same.


Bioavailability of different CBD products


There are hundreds of different CBD products available, but they're all consumed in one of five ways: inhaled, absorbed under the tongue, eaten, inserted rectally, or applied to the skin.

Although each technique delivers CBD to your body, the rate of absorption varies.

Various products give different percentages of the original measure to your blood.

It's also likely that the time it takes for you to notice any effect may vary.

Inhaling the vapor through a vaporizer, which can deliver up to 56 percent of each dose to your circulation, is the most efficient approach for CBD absorption.

However, when CBD is absorbed under the tongue, the effects are longer-lasting.




CBD dose and absorption are inextricably linked.

That means that if you take a higher dose, a greater amount of CBD will enter your system.

CBD dose has been shown to increase or triple the bioavailability of cannabinoids in studies.

Remember to start with small dosages of CBD oil and gradually increase your dosage over time as you figure out what works best for you.




Every organism is different, and that is why the dosage is not the same for everyone. You have to discover what works best for you, and your body.

Our Gramina team is here to help you along the process.

Contact us if you have any questions about the right dosage for you or anything else.

Head to our SHOP to order your first Gramina CBD Oil bottle, and start experiencing the first benefits of CBD Oil.


Shop now

You can use this element to add a quote, content...